Buy Pentosan Injection 50ml online.
Buy Pentosan Injection 50ml online is a concentrated anti-inflammatory and stimulant of cartilage synthesis, repair and protection.
What is Pentosan Injection?
PENTOSAN INJECTION is a concentrated anti-inflammatory and stimulant of cartilage synthesis, repair and protection (250mg/mL).
Composition: Contains: Sodium pentosan polysulfate 250 mg/ml.
Features and Benefits: Buy Pentosan Injection 50ml online.
Sodium pentosan polysulfate (PPS) is a linear polymer prepared from xylan, a complex hemicellulose extract of the plant (Beechwood) origin.
PPS is one of the sulfated heparinoid compounds. The heparin-like anti-coagulant effects have been reduced and the anti-inflammatory, fibrinolytic and tissue trophic effects have been enhanced.
PENTOSAN INJECTION actively reverses the effects of osteoarthritis in the joints via a series of actions including:
1. Stimulating Chondrocyte Metabolism: Results in increased production of proteoglycans and healthy cartilage matrix. PPS stimulates synovial fibroblasts and produces an increased amount of high molecular weight hyaluronic acid which results in an increased production of normally viscous joint fluid.
Improving the fluid volume and consistency results in more effective joint lubrication and also stabilization, which limits further cartilage damage.
2. Anti-inflammatory Activity: PPS has an inhibitory action on all mediators of the arachidonic acid cascade. PPS also inhibits the lysosomal catabolic enzymes histamine, hyaluronidase, cathepsin B, and polymorphonuclear elastase.
PPS exerts a specific inhibitory effect on mediators implicated in the degradation of cartilage matrix components, preserving the cartilage and thus preventing the release of the highly inflammatory mediators, which relieves pain and inflammation.
3. Fibrinolysis and Lipolysis: PPS is strongly fibrinolytic, stimulating the release of plasminogen activator and promotes the dissolution of thrombi and fibrin deposits in synovial tissues and subchondral blood vessels.
Dosage and Administration:
Administer at a dose rate of 3 mg/kg bodyweight by intravenous injection at 5-7 day intervals for four injections.
If intra-articular use is require.
Non-infectious inflammatory joint disease, traumatic arthritis, osteoarthritis, degenerative cartilaginous joint disease and osteochondrosis dessicans in horses.