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Buy Yohimbine A 10ml Online is a specific α2A-adrenoreceptor antagonist with central action. It is an effective antagonist to xylazine in horses and camels.
What is Yohimbine A?
Yohimbine A is an alpha-2 adrenergic receptor antagonist, is an indole alkaloid found in numerous botanical sources.
It is the predominant alkaloid in extracts from the bark of the Pausinystalia yohimbe tree, and can also be found in Rauwolfia root.
Yohimbine has two stereoisomers rauwolscine that differ little in their physical properties or in their effects on serotonin and dopamine receptors.
The three isomers, however, do differ significantly in their affinity for the alpha-1 and alpha-2 adrenergic receptor subtypes.
It was one of the first radioligands developed for selectively labeling alpha-2 adrenergic receptors.
HOW DOES IT WORK? Buy Yohimbine A 10ml Online
Yohimbine works by blocking receptors in the body called alpha-2 adrenergic receptors.
These receptors play an important role in inhibiting erections. Therefore, yohimbine is thought to help alleviate erectile dysfunction by blocking the receptors responsible for preventing erections.
Yohimbine may also promote the release of nitric oxide. This could lead to the dilation of blood vessels and an increase in blood flow to sexual organs.
WHY USE Yohimbine A?
Yohimbine is one of the most specific α2A-adrenoreceptor antagonist itself well to antagonism.
It is an effective antagonist to xylazine in horses and camels. In horse, yohimbine hydrochloride is an effective antagonist to xylazine sedation in red, fallow.
In horse, yohimbine hydrochloride is an effective antagonist to xylazine sedation in red, fallow. camel, yohimbine has been found to effectively reverse xylazine sedation.
Yohimbine overdose does not cause central excitation but instead produces sedation.
Administration and Dosage:
Give by intravenous injection only. 1mL/40kg (0.25 mg/kg) bodyweight; mature animals: 1mL/50kg (0.2mg/kg) bodyweight.
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Yohimbine is a drug used in veterinary medicine to reverse the effects of xylazine in dogs and deer.
It is used as a research reagent.
In the US, it is prescribed, but now rarely, for erectile dysfunction in men.
While yohimbine behaves as an aphrodisiac in some mammals, it does not do so in humans.
It has been prescribed as a treatment for erectile dysfunction, but its reported clinical benefits were modest and it has largely been superseded by the PDE5 inhibitor class of drugs.
Substances that have purported to be extracts from the yohimbe tree have been marketed as dietary supplements for various purposes, but they contain highly variable amounts of yohimbine, if any; no published scientific evidence supports their efficacy.
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